METABOLISME LEMAK

PERTEMUAN KE 10

METABOLISME LEMAK

Pengangkutan lemak di dalam darah melalui 2 jalur, yaitu :
1. Jalur Eksogen
2. Jalur Endogen

Trigliserida dan kolesterol yang berasal dari makanan dalam usus dikemas dalam bentuk partikel besar lipoprotein yang disebut kilomikron. Kilomikron membawa lemak ke dalam aliran darah.

Trigliserida mengalami penguraian oleh enzim lipoprotei lipase membentuk asam lemak bebas dan kilomikron remnan.

Sebagian kolesterol ada yang diubah menjadi asam empedu yang dikeluarkan ke dalam usus, sebagian lagi dikeluarkan melalui saluran empedu tanpa dimetabolisme menjadi asam empedu, selanjutnya hati akan mendistribusikan kolesterol ke jaringan tubuh lainnya melalui jalur endogen.

Metabolisme lemak secara lengkap dapat dibaca pada artikel :
A Quick Look at Biochemistry : Lipid Metabolism (Monireh Dashty) (Open Access)

Proses Oksidasi Asam Lemak :


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